Simone Graber, Ph.D., Mary E. Morrison, Ph.D., and Shelley Halpain, Ph.D.
Dr. Graber is a Postdoctoral Associate, The Burnham Institute, Center for Neuroscience and Aging, La Jolla, CA, and Drs. Morrison and Halpain are, respectively, Staff Scientist and Associate Professor, The Scripps Research Institute, Department of Cell Biology and Institute for Childhood and Neglected Diseases, La Jolla, CA.
Drs. Graber, Morrison, and Halpain report no commercial conflict of interest.
This activity is made possible by an unrestricted educational grant from Forest Laboratories.
Estimated course time: 1 hour(s).
Albert Einstein College of Medicine – Montefiore Medical Center designates this enduring material activity for a maximum of 1.0 AMA PRA Category 1 Credit(s)™. Physicians should claim only the credit commensurate with the extent of their participation in the activity.
In support of improving patient care, this activity has been planned and implemented by Albert Einstein College of Medicine-Montefiore Medical Center and InterMDnet. Albert Einstein College of Medicine – Montefiore Medical Center is jointly accredited by the Accreditation Council for Continuing Medical Education (ACCME), the Accreditation Council for Pharmacy Education (ACPE), and the American Nurses Credentialing Center (ANCC), to provide continuing education for the healthcare team.
Upon completion of this Cyberounds®, you should be able to:
Define dendritic spines and understand the concept of biochemical compartmentalization
Discuss the correlation between changes in spine shape/function and disease states
Discuss spine loss in the context of excitotoxicity.