Chaim Putterman, M.D., and Peter Barland, M.D.
Dr. Putterman is Assistant Professor of Medicine at the Albert Einstein College of Medicine and the Director of the Arthritis Clinic at Montefiore Medical Center. Drs. Putterman and Barland report no commercial conflicts of interest.
Estimated course time: 1 hour(s).
Albert Einstein College of Medicine – Montefiore Medical Center designates this enduring material activity for a maximum of 1.0 AMA PRA Category 1 Credit(s)™. Physicians should claim only the credit commensurate with the extent of their participation in the activity.
In support of improving patient care, this activity has been planned and implemented by Albert Einstein College of Medicine-Montefiore Medical Center and InterMDnet. Albert Einstein College of Medicine – Montefiore Medical Center is jointly accredited by the Accreditation Council for Continuing Medical Education (ACCME), the Accreditation Council for Pharmacy Education (ACPE), and the American Nurses Credentialing Center (ANCC), to provide continuing education for the healthcare team.
Upon completion of this Cyberounds®, you should be able to:
Describe the role of TNF and IL-1b in the pathogenesis of rheumatoid arthritis
Discuss the mechanism of action, dosing, major side effects and indications for the use of leflunomide, infliximab, etanercept and anakinra in rheumatoid arthritis
Enumerate the differences between infliximab and etanercept
Discuss the potential effects of biologic agents on structural damage to cartilage and bone in rheumatoid joints.